| Fecha | Local | Visitante | Resultado |
|---|---|---|---|
| 11/12/24 16:30 | Fenerbahçe SK | Athletic Club | 0:2 |
| 12/12/24 18:45 | Malmö FF | Galatasaray Estanbul | 2:2 |
| 12/12/24 18:45 | AS Roma | Sporting Braga | 3:0 |
| 12/12/24 18:45 | PAOK Salónica | Ferencvaros Budapest | 5:0 |
| 12/12/24 18:45 | Olympiacos Piräus | FC Twente Enschede | 0:0 |
| 12/12/24 18:45 | Royale Union Saint-Gilloise | OGC Niza | 2:1 |
| 12/12/24 18:45 | PFC Ludogorets Razgrad | AZ Alkmaar | 2:2 |
| 12/12/24 18:45 | Viktoria Pilsen | Manchester United | 1:2 |
| 12/12/24 18:45 | 1899 Hoffenheim | FCSB Bukarest | 0:0 |
| 12/12/24 21:00 | Glasgow Rangers | Tottenham | 1:1 |
| 12/12/24 21:00 | FC Porto | FC Midtjylland | 2:0 |
| 12/12/24 21:00 | Slavia Praga | RSC Anderlecht | 1:2 |
| 12/12/24 21:00 | Ajax Amsterdam | Lazio Roma | 1:3 |
| 12/12/24 21:00 | Maccabi Tel Aviv | Rigas Futbola Skola | 2:1 |
| 12/12/24 21:00 | Real Sociedad de Fútbol | Dinamo de Kiev | 3:0 |
| 12/12/24 21:00 | Olympique Lyon | Eintracht Frankfurt | 3:2 |
| 12/12/24 21:00 | FK Bodö/Glimt | Besiktas JK | 2:1 |
| 12/12/24 21:00 | IF Elfsborg Boras | Qarabag | 1:0 |